Due to its asymptomatic characteristic, it is difficult to diagnose and prevent hypertension before its complications occur.Īccording to the American College of Cardiology/American Heart Association (ACC/AHA) 2017 guideline, the blood pressure target of the criteria for diagnosis of hypertension had changed to a systolic and diastolic blood pressure (BP) of less than 130 mmHg and 80 mmHg, respectively. Hypertension contributes to the global burden of disease and has long been called a silent killer, having no special symptoms during its progression. We suggest that the strategies necessary to prevent progression to stage 2 hypertension need to be set differently for each target course. This study found that the incidence of hypertension is associated with the progression at each stage. The mean years of progression from normal blood pressure to stage 2 hypertension were 8.7☒.6 years (course A), 6.1☒.9 years (course B), 7.5☒.8 years (course C) and 3.2☒.0 years, respectively. After the follow-up period, 77.5% ( n=3879) of participants with stage 2 hypertension were found to be course C ( n= 2378) and D ( n=1501).
In particular, over 60 years old had a 2.8-fold higher incidence of stage 2 hypertension than 40–49 years old. Resultsĭuring the median 12.23 years of follow-up period, 52.8% ( n= 11,168) and 23.6% ( n=5004) of the participants had stage 1 and stage 2 hypertension, respectively. We classified the participants into four courses (Course A: normal BP → elevated BP → stage 1 hypertension→ stage 2 hypertension, Course B: normal BP → elevated BP → stage 2 hypertension, Course C: normal BP → stage 1 hypertension → stage 2 hypertension, Course D: normal BP → stage 2 hypertension) according to their progression from normal blood pressure to stage 2 hypertension. The criteria for blood pressure were based on the American College of Cardiology/American Heart Association 2017 guideline (normal BP: SBP < 120 and DBP < 80 mmHg, elevated BP: SBP 120–129 and DBP < 80 mmHg, stage 1 hypertension: SBP 130–139 or DBP 80–89 mmHg, stage 2 hypertension: SBP ≥140 or DBP ≥ 90 mmHg).
We selected a total of 21,172 normotensive individuals between 20 from the National Health Insurance Service-Health Screening and followed them up until 2015.
The study aimed to estimate the incidence of and period of progression to stage 2 hypertension from normal blood pressure.
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